Blood Clotting Essay

Coagulation, or thrombogenesis, is the process by which p arnthood change states in an attempt to restrict birth loss from an psychic trauma billet, and repair the damaged vessel. Most of the time turn is a good thing, however there argon circumstances when a overload can frame of reference abnormally, leading to heart attack, stroke, or other grievous medical problems. A gunstock curdle forms more or less immediately after the bleeding occurs, which is possible by way of life of enzymes and other substances in assembly line that respond to breaks in vessel walls. The change state is a temporary put in preventing further blood loss. There ar quartette major parts of blood clot formation. The start-off step in clot is the formation of the platelet plug. Platelets ar the smallest of the three major types of blood cells whose master(a) function is to prevent bleeding.When encountering a damaged blood vessel, the platelets become stimulated and rush to the injury office where they clump together, forming a plug and restricting the bleeding. They likewise release substances to begin the chemical reaction of the turn process. These chemical reactions are responsible for growing the blood clot. Dissolved proteins, also referred to as clotting factors, are contained within the blood for the purpose of promoting blood clots. These proteins transfer signals to each other and enhance each others activity exponentially at the site of injury, resulting in a rapid chemical chain reaction which produces fibrin, the main protein forming clots. This blood clot make with fibrin is tougher and more durable than the platelet plug. once the blood clot forms, it is important that it not grow and circularise to the rest of the body, which can cause serious damage. This is where anti-clotting comes in to play. Proteins such as antithrombin, protein C, and protein S, are known anti-clotting proteins and equal in a natural balance with the clotting factor s. These substances work to neutralize excess clotting factors, preventing the clot from going to places it should not. The final part of the process is where the clot is slowly broken down by the body. Once the damaged tissue heals, the body gradually degrades the clot and reabsorbs it. The tough fibrin strands in a blood clot are dissolved by an enzyme called plasmin. Plasmin is trigger off by other substances working together to attend the clot break down.The whole process of blood clotting is whenever the blood is exposed to certain substances. These are known as thrombogenic substances because they promote the formation of thrombus (clot). galore(postnominal) of these substances, such as tissue factor, collagen, and von Willebrand factor, are located in the skin or in the blood vessel walls, typically separated from current blood. If they come into contact with flowing blood, this typically means the blood vessel wall is ruptured and bleeding. A clot may also form when blood is not flowing properly. http//www.hematology.org/patients/blood-disorders/blood-clots/5233.aspx http//www.webmd.com/a-to-z-guides/blood-clots